Endocrine Abstracts

Introduction: Extramedullary hematopoiesis (EMH) is most commonly seen in reticuloendothelial system tissues such as liver, spleen and lymph nodes. Rarely, it can be detected in non-hepatosplenic atypical localizations such as the adrenal glands. Although the underlying mechanism is not clearly elucidated, it is suggested that the adrenal glands have hematopoietic activity in the fetal period and EMH may develop from the remains here due to chronic anemia. We aimed to present ...

Introduction: Hemiballism is a rare hyperkinetic movement disorder characterized by involuntary, violent, coarse and wide-amplitude movements involving the ipsilateral arm and leg. Here, we aimed to present a case diagnosed as hemiballism due to non-ketotic hyperglycemia.Case Report: A 60-year-old female patient presented to the emergency department with involuntary movements in the right half of the trunk for 10 days. It was a large amplitude proximal e...

Introduction: Although ectopic ACTH syndrome (EAS) is most commonly seen in cancers with neuroendocrine differentiation, it is not a common condition in germ cell tumors. Here we report a rare case of EAS due to metastatic germ cell tumor.Case report: A 53-year-old male patient presented with fatigue, weakness, swelling in both legs and weight loss for 3 months. He had type 2 diabetes and no history of smoking or alcohol. In the physical examination, the...

Introduction: Glucagonomas are rare neuroendocrine tumours (NET). Glucagonoma syndrome is often misdiagnosed as other skin lesions by clinicians due to typical clinical sign of necrolytic migratory erythema (NME). In this article, we report a metastatic glucagonoma case diagnosed at adult age with distinct features of the disease.Observations: We present a case of a 28-year-old female patient. The initial rash appeared in early 2019 and was mostly on low...

Introduction: Pituitary apoplexy is a life-threatening clinical syndrome that develops as a result of bleeding or infarction in a pituitary adenoma. Here, we aimed to present a case of cabergoline-resistant macroprolactinoma who developed pituitary apoplexy.Case Report: A 40-year-old male patient presented to neurology 2 years ago with severe headache. Brain magnetic resonance imaging (MRI) revealed a 15.5×18×21 mm macroadenoma in the pituitary...

A 48-year-old male presented with headache, cough and recurrent nose bleeds. Clinical examination showed saddle shape nose deformity. His past medical history included primary hypothyroidism diagnosed at the age of 10 years, was taking levothyroxine. His brother had a Rathke’s cleft cyst, surgically removed. His blood test were as follows: Sodium 125mmol/l, TSH 0.10mU/l, free T4 10.2pmol/l, freeT3 2.6pmol/l, cortisol < 28nmol/l, prolactin 240mU/l, FSH 1.8U/l, LH 0.3U/...

Introduction: Germinomas, which are the most common germ cell tumors of the central nervous system, may present with different symptoms depending on the location and are localized in the 20-30% suprasellar region. Here, we aimed to present a case of suprasellar germinoma with central diabetes insipidus, hypogonadism and secondary adrenal insufficiency.Case Report: A 27-year-old male patient presented with dry mouth, polydipsia, polyuria and nocturia for ...

Objectives: Primary thyroid lymphoma constitutes 0.5-5% of all thyroid malignancies. Its incidence is two per million persons. Patients usually present with rapidly growing masses in the thyroid their sixth-seventh decades. The disease is frequently accompanied by chronic Hashimoto’s thyroiditis. Most tumors are B-cell derived non-Hodgkin’s lymphoma.Case report: An 84-year-old male patient presented with a palpable swelling in the neck. Ultraso...

Aims: Glycosylated hemoglobin (HbA1c) is a marker which demonstrates 3-month average level of blood glucose level. In individuals with high blood sugar level for a long time is associated with increased risk of cardiovascular disease (CVD). There is a need for simple and cost-effective markers to determine the risk of CVD in primary health care settings. In this study, we aimed to investigate the value of HbA1c for predicting cardiovascular risk in healthy non-diabetic individ...

A 45-year-old female presented with secondary amenorrhea. Since menarche, her period has been irregular, which she initially managed with oral pills, which were discontinued in 2009. Subsequently, she does have complete secondary amenorrhoea. She has hirsutism at the age of 20. Which was initially well controlled with oral contraceptive pills but has been getting worse over the years. Ferriman-Gallwey’s score was high. She also stated that her weight had been steadily inc...